Séances du jeudi matin de 10h à 12h (alternées entre ICJ, UMPA, Institut Fourier)
- 15 mai 2025 à Lyon (ICJ)
- Laetitia Colombani (ISFA, Lyon): Interacting birth-death processes in adaptation to an environmental change and their lineages
- Abstract: In the last decades, environmental changes and the consequences of the evolution of the population, especially the phenotypic evolution, have been described by different models. In this ongoing study, with Tran and Méléard, we aim to understand the individual dynamics of a population. In particular, we want to describe the ancestral lineage of a living individual. Some preliminary work has been published by Calvez, Henry, Méléard and Tran in 2022 when the initial population is well distributed and is close to the stationary solution of a PDE.
In this talk, I will introduce the model, its construction, and the link with the PDE of the macroscopic dynamics of the phenotypic density. I’ll then describe some of the results we obtain when we consider any initial repartition of the population.
- Abstract: In the last decades, environmental changes and the consequences of the evolution of the population, especially the phenotypic evolution, have been described by different models. In this ongoing study, with Tran and Méléard, we aim to understand the individual dynamics of a population. In particular, we want to describe the ancestral lineage of a living individual. Some preliminary work has been published by Calvez, Henry, Méléard and Tran in 2022 when the initial population is well distributed and is close to the stationary solution of a PDE.
- Rémi Tuffet (LBBE, Lyon): The Paradox of Plasmid Diversity
- Abstract: Plasmids are circular DNA molecules independent of the bacterial chromosome that can be transferred horizontally between bacteria in an autonomous manner. As such, they are the main vector for horizontal gene transfer between bacteria. In particular, they are responsible for the rapid dissemination of many antibiotic resistance genes, as well as some virulence genes. Plasmids are therefore a threat to our healthcare systems, and it is essential to better understand their eco-evolutionary dynamics.
Having established that there is a wide diversity of plasmids, just as there can be a great diversity of interacting species in communities, we propose to apply the theories and concepts of community ecology to bacterial plasmids. In particular, we develop models of competition between plasmids to illustrate how the three main theories of biodiversity (ecological niche partitioning theory, neutral biodiversity theory and emergent neutrality theory) can be applied to plasmids.
- Abstract: Plasmids are circular DNA molecules independent of the bacterial chromosome that can be transferred horizontally between bacteria in an autonomous manner. As such, they are the main vector for horizontal gene transfer between bacteria. In particular, they are responsible for the rapid dissemination of many antibiotic resistance genes, as well as some virulence genes. Plasmids are therefore a threat to our healthcare systems, and it is essential to better understand their eco-evolutionary dynamics.
- Laetitia Colombani (ISFA, Lyon): Interacting birth-death processes in adaptation to an environmental change and their lineages
- 3e journée : 6 juin 2025 à Grenoble (journée soutenue par le RT Math Bio Santé)
- Sophie Achard (LJK, Grenoble)
- Thomas Lepoutre (Inria, Lyon)
- Magali Richard (TIMC, Grenoble)
- Charline Smadi (INRAE, IF, Grenoble)
